Jervine

• Background:

  Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 μM) . Binds directly to Smoothened (Smo) 1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3.

• Conjugation:

  Unconjugated

• Buffer:

  White solid

• Storage Conditions:

  -20°C