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Leflunomide

CAT: 0498-bs-82474C-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82474C-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug) 1. Displays immunomodulatory activity inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) 2. Although the molecule directly responsible for DHODH is actually A77 1726, a metabolite of Leflunomide. Rescues mice from acetaminophen-induced liver injury3.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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