Ansamitocin P3

• Background :

  Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4.

• Conjugation :

  Unconjugated

• Buffer :

  Yellow solid

• Storage Conditions :

  -20°C