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Lenalidomide

CAT: 0498-bs-82415C-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82415C-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thalidomide analog which, like thalidomide,1 binds to cereblon which is the substrate recognition component of a cullin-dependent ubiquitin ligase and inhibits its autoubiquitination activity2. Induces degradation of T-cell repressors Ikaros (IKZF1) and Aiolos (IKZF3) leading to T cell activation2. Selective inhibition of IKZF1 and IKZF3 in multiple myeloma cells results in cell death3,4. Cell permeable. Caution: Teratogenic
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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CatalogName
FL24864-01Lenalidomide

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