Products for Research Use Only

Bexarotene

CAT: 0498-bs-82399C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82399C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRα, β, γ respectively) 1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble β-amyloid in a mouse Alzheimer′s model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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