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Axitinib

CAT: 0498-bs-82398C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82398C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent inhibitor of VEGFR-2, -3, and -1, IC50 = 0.2, 0.1-0.3, and 1.2 nM respectively1 displaying minimal activity against a panel of ~100 protein kinases. Inhibits angiogenesis and vascular permeability.2 Also inhibits BCR-ABL1 (T315I) with high potency, Ki = 149 pM for autophosphorylated ABL1 (T315I) .3 Inhibits proliferation of Ba/F3 cells expressing BCR-ABL1 (T315I) . Clinically useful anticancer agent.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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CatalogName
HY-10065-01Axitinib

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