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Thiostrepton

CAT: 0498-bs-82393C-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0498-bs-82393C-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU (GTP) -catalyzed aa-tRNA delivery as well as the activity of initiation factor-1 (IF-2) 1-2. Displays antitumor activity. Induces apoptosis and cell cycle arrest in various tumor cells via downregulation of FOXM1 expression3.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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CatalogName
T1679-01Thiostrepton

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