Mithramycin A

CAT:
498-bs-82383C-01
Size:
1 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Mithramycin A - image 1

Mithramycin A

  • Background :

    Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.
  • Conjugation :

    Unconjugated
  • Buffer :

    Yellow solid
  • Storage Conditions :

    -20°C

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