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Mithramycin A

CAT: 0498-bs-82383C-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82383C-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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