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Cerulenin

CAT: 0498-bs-82373C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82373C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM1. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors2. Reduces nutrient-induced insulin release from normal rat islets3. Induces apoptosis in human melanoma A-375 cells4.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

Alternative Products

CatalogName
FC162600-01Cerulenin
444218-01Cerulenin (Synthetic)

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