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Compound 115-7c

CAT: 0498-bs-82324C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: bs-82324C-01Size: 5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as an artificial co-chaperone for HSP701. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau2. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity3,4. An important probe for understanding HSP70 functions4
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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