Ro 31-8425 HCl

CAT: 0498-bs-82322C-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-82322C-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCα, β1, β2, γ and ε, IC50= 8, 8, 14,13 and 39 nM respectively.1 Extremely useful tool for probing PKC-dependent physiology2 or signaling pathways3. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner.4 Cell permeable.

Conjugation

Unconjugated

Buffer

Red solid

Storage Conditions

-20°C

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Ro 31-8425 HCl

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