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Fascaplysin

CAT: 0498-bs-82298C-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82298C-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM) . Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
Conjugation
Unconjugated
Buffer
Dark red-brown solid
Storage Conditions
-20°C

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