HIF-2α-I2

CAT: 0498-bs-82290C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82290C-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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