TC-E 5003

• Background:

  Selective protein arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 μM. Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Blocks androgen-induced gene expression in LNCaP cells1.

• Conjugation:

  Unconjugated

• Buffer:

  Brown solid

• Storage Conditions:

  -20°C