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LY-364947

CAT: 0498-bs-82281C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82281C-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.
Conjugation
Unconjugated
Buffer
White or slightly yellow solid
Storage Conditions
RT

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