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Salirasib

CAT: 0498-bs-82258C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82258C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 µM) .7
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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