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Gue1654

CAT: 0498-bs-82236C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82236C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170) 1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid2. It selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R.1,3 Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model.4
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

Alternative Products

CatalogName
M34274-01Gue1654
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