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CZC-54252

CAT: 0498-bs-82233C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82233C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM) 1. The G2019S mutant is a common mutation found in familial Parkinson’s disease patients2. Cell permeable.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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