Fatostatin

• Background:

  Blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP) . Prevents increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice1. Inhibits high glucose-induced TGF-β in mesangial cells2. Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  Yellow solid

• Storage Conditions:

  RT