K-858

CAT: 0498-bs-82170C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82170C-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Selective mitotic kinesin Eg5 inhibitor (IC50 = 1.3 μM) which acts in an ATP-noncompetitive manner1,2. It is at least 150-fold more selective for Eg5 than other members of the kinesin superfamily. K858 blocks centrosome separation, activates the spindle checkpoint and induces mitotic arrest accompanied by the formation of monopolar spindles. Displays no effect on microtubule polymerization. Selectively displays antiproliferative effects via induction of mitotic cell death in cancer cells over nontransformed cells1.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

Related Products

CatalogName
bs-7190C-01K 03861
bs-75080C-01K-252c
bs-5823RK Cadherin Polyclonal Antibody
bsm-61246R-TRHnRNP K Recombinant Antibody
bsm-61762R-01K Cadherin Recombinant Antibody
bs-6788R-TRGranzyme K Polyclonal Antibody
bs-6788R-01Granzyme K Polyclonal Antibody
bs-7887R-TRCyclin K Polyclonal Antibody
bsm-61246R-01HnRNP K Recombinant Antibody
bs-1611RCathepsin K Polyclonal Antibody

Alternative Products

CatalogName
MBS384974-01K 858
abx282229-01K-858
A15844-50K 858 50mg
A15844-100K 858 100mg
255579-01K 858 discontinued
A15844-10K 858 10mg
A15844-5K 858 5mg
A15844-25K 858 25mg
TBI1312-25MGK-858, Kinesin Eg5 inhibitor
A15844-10mM-DK 858 10mM * 1mL in DMSO

Popular Products