BRL-50481

• Background:

  Potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM1. Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B2. Increases mineralization in osteoblasts differentiated from hMSC3. Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  Off-white solid

• Storage Conditions:

  RT