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Cytarabine

CAT: 0498-bs-82148C-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82148C-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML) .6,7
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C

Alternative Products

CatalogName
A8405-1000Cytarabine

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