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IU1

CAT: 0498-bs-82128C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82128C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Selective inhibitor of Usp14 (IC50<4 μM) . Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

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