AP-18

CAT: 0498-bs-82082C-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-82082C-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

TRPA1 channel blocker IC50=3.1-4.5 μM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 μM.1 Blocks TRPA1 pore dilation (IC50=10.3 μM) .2 An important tool for assessing the role of TRPA1 in cell signaling and physiological processes.3-5

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

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AP-18

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