SP-600125

CAT: 0498-bs-82020C-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82020C-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Selective inhibitor of c-Jun N-terminal kinase (JNK) . Reversibly inhibits JNK1,2 and 3 (IC50’s range from 40-90 nM) . >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
RT

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