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LFM-A13

CAT: 0498-bs-82019C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82019C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LFM-A13 is a selective inhibitor of Bruton’s tyrosine kinase (BTK) – IC50’s = 2.5 µM (recombinant BTK) and 17.2 µM (human BTK) .1,2 It has also been shown to inhibit Polo-ilke kinase (PLK) – IC50 = 61 µM for human PLK3.3 It displayed no activity (concentrations up to 278 µM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten tyrosine kinases3.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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