ZM-336372

CAT: 0498-bs-82017C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82017C-01Size:5 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM) . Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2α) (IC50=2µM) and SAPK2β (p38β) (IC50=2µM) . Induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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