Products for Research Use Only
RegisterLogin

Garadacimab

CAT: 0804-HY-P99631-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P99631-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Garadacimab (CSL312) is a first-in-class, fully human IgG4 monoclonal antibody targeting activated factor XII (FXIIa) . Garadacimab has the potential for hereditary angioedema research[1].
CAS Number
2162134-62-3
Product Name Alternative
CSL312
UNSPSC
12352203
Target
Factor Xa
Type
Inhibitory Antibodies
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/garadacimab.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
[Garadacimab]
Molecular Weight
(146.5 kDa)
References & Citations
[1]Dipti Pawaskar, et al. Pharmacokinetic/pharmacodynamic modeling for dose selection for the first-in-human trial of the activated Factor XII inhibitor garadacimab (CSL312) . Clin Transl Sci. 2022 Mar;15 (3) :709-720. |[2]Helen Cao, et al. Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation. J Allergy Clin Immunol. 2018 Oct;142 (4) :1355-1358.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 4

Alternative Products

CatalogName
abx831519-01Garadacimab
591885Garadacimab (F12)
GTR18337750-01Garadacimab Antibody
E55B0509Garadacimab (Reference antibody)
WA2898Research Grade Garadacimab
KBI1352KRIBIOLISA™ Garadacimab ELISA
ICH5563-20mgGaradacimab Biosimilar - Research Grade
GTR18697672-01Garadacimab Human Monoclonal Antibody
GTR18780550-01(Garadacimab) Biosimilar Reference Antibody
A138280Garadacimab Biosimilar (Monoclonal, IgG4)

Popular Products