Phospho-c-Kit Antibody (pY823)

• Description:

  This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

• Specifications:

  Dot blot: 1:500

• UniProt:

  P10721

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This phospho-c-Kit antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY823 of human c-Kit.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  DB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Limitations:

  This phospho-c-Kit antibody is available for research use only.

• Storage Conditions:

  Aliquot the phospho-c-Kit antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the phospho-c-Kit antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Bovine, Pig

• Image Legend:

  Dot blot analysis of phospho-c-Kit antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.