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ATP7B Antibody

CAT: 0800-F54249-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54249-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATP7B is a member of the P-type cation transport ATPase family and a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile.
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-1:50, Immunofluorescence: 1:25
UniProt
P35670
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 1361-1391 from the human protein were used as the immunogen for the ATP7B antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS, IF
Purity
Protein A purified
Format
Purified
Limitations
This ATP7B antibody is available for research use only.
Storage Conditions
Aliquot the ATP7B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the ATP7B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of 1) human Caco-2, 2) mouse kidney and 3) rat liver lysate with ATP7B antibody. Expected molecular weight: 140-157 kDa.

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