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RYK Antibody

CAT: 0800-F54254-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54254-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
Specifications
Western blot: 1:1000, Immunohistochemistry (FFPE) : 1:50-1:100
UniProt
P34925
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 160-190 from the human protein were used as the immunogen for the RYK antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Limitations
This RYK antibody is available for research use only.
Storage Conditions
Aliquot the RYK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the RYK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human ovary lysate with RYK antibody. Predicted molecular weight ~68 kDa.

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