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MyD88 Antibody

CAT: 0800-F55059-0.05MLSize: 0.05 mLDry Ice: NoHazardous: No
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CAT#:0800-F55059-0.05MLSize:0.05 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Myeloid differentiation primary response protein MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:10-1:50, Flow Cytometry: 1:10-1:50 per million cells in 0.1ml
UniProt
Q99836
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This MyD88 antibody is available for research use only.
Storage Conditions
Aliquot the MyD88 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
MyD88 antibody flow cytometric analysis of fixed and permeabilized human K562 cells (green) compared to a negative control (blue) . FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.

UniProtKB · Q99836

Myeloid differentiation primary response protein MyD88

MYD88_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99836
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYD88
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DKH8, B4DKU4, B4DQ60, B4DQ72, J3KPU4, J3KQ87, J3KQJ6, P78397, Q53XS7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseImmunityInflammatory responseInnate immunity

Cellular component

CytoplasmNucleus

Disease

Disease variant

PTM

PhosphoproteinUbl conjugation

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10R-8668MYD88 antibody

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