Products for Research Use Only
RegisterLogin

BAX Antibody

CAT: 0800-F55072-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F55072-0.1MLSize:0.1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Apoptosis is a highly regulated process that is essential for the development and maintenance of multicellular organisms. The BAX protein is a crucial regulator of apoptosis, promoting cell death by permeabilizing the mitochondrial outer membrane and initiating the release of cytochrome c, which triggers a cascade of events leading to cell death. With its ability to induce apoptosis, the BAX protein acts as a safeguard against abnormal cell growth and development, ultimately ensuring cellular homeostasis. The activity of the BAX protein is tightly regulated by a variety of factors, including interactions with other proteins, post-translational modifications, and subcellular localization. Dysregulation of BAX activity can have serious consequences, leading to various diseases such as cancer, neurodegenerative disorders, and autoimmune diseases.
Specifications
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100, Immunofluorescence: 1-50-1:100
UniProt
Q07812
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 51-79 from the human protein was used as the immunogen for the BAX antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, IF
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This BAX antibody is available for research use only.
Storage Conditions
Store the BAX antibody at -20°C.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide and 50% glycerol
Applications Notes
Titration of the BAX antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasm, Nucleus
Image Legend
Western blot testing of human 1) 293 and 2) HT-1080 cell lysate with BAX antibody. Predicted molecular weight ~21 kDa.

UniProtKB · Q07812

Apoptosis regulator BAX

BAX_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q07812
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BAX
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K4W1, P55269, Q07814, Q07815, Q8WZ49, Q9NR76, Q9NYG7, Q9UCZ6, Q9UCZ7, Q9UQD6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisHost-virus interaction

Cellular component

CytoplasmMembraneMitochondrionMitochondrion outer membraneNucleus

Domain

TransmembraneTransmembrane helix

Disease

Tumor suppressor

Related Products

CatalogName
V5784-100UGRecombinant BCL2L4 Antibody / BAX
V5784-20UGRecombinant BCL2L4 Antibody / BAX
V5784SAF-100UGRecombinant BCL2L4 Antibody / BAX
RQ7366BI-1 Antibody / Bax inhibitor 1 / TMBIM6
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.2MLAntibody
F53954-0.05MLAntibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody

Alternative Products

CatalogName
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
DF8746-01ASAP1 antibody Antibody
E36403ZNF98 Antibody Antibody
GWB-250026Lck antibody Antibody
E8M1007-4HSP60 Antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
GWB-5C6547MAD1L1 antibody [9B10] Antibody

Popular Products