NUAK1 Antibody / ARK5

• Description:

  NUAK1, also known as AMPK-related protein kinase 5 (ARK5), is a key player in regulating energy metabolism and cell survival. It has been linked to various cellular processes, including cell proliferation, autophagy, and the response to stress. Studies have shown that NUAK1 may be involved in the development of certain cancers, making it a promising target for anti-cancer therapies. Additionally, NUAK1 has been linked to conditions such as diabetes and neurodegenerative diseases, suggesting that it could have implications for a wide range of health conditions.

• Specifications:

  Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100

• UniProt:

  O60285

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 604-634 from the human protein was used as the immunogen for the NUAK1 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, IHC-P

• Format:

  Purified

• Limitations:

  This NUAK1 antibody is available for research use only.

• Storage Conditions:

  Aliquot the NUAK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the NUAK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Location:

  Cytoplasm, Nucleus

• Image Legend:

  IHC staining of FFPE human breast cancer tissue with NUAK1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.