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WNT5A Antibody

CAT: 0800-RQ8728Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8728Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene. This gene is a member of the WNT gene family. The WNTs comprise a large class of secreted proteins that control essential developmental processes such as embryonic patterning, cell growth, migration, and differentiation. It is mapped to 3p14.3. WNT5A is highly expressed in the dermal papilla of depilated skin. This protein plays an essential role in regulating developmental pathways during embryogenesis. And this protein may also play a role in oncogenesis. WNT5A and DVL can promote axon differentiation mediated by the PAR3-PAR6-aPKC complex.
Specifications
Western blot: 1-2 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
P41221
Host
Rabbit
Reactivity
Human
Immunogen
An E.coli-derived human recombinant protein (amino acids D198-D303) was used as the immunogen for the WNT5A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This WNT5A antibody is available for research use only.
Storage Conditions
After reconstitution, the WNT5A Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the WNT5A antibody should be determined by the researcher.
Image Legend
Western blot testing of human SiHa cell lysate with WNT5A antibody. Predicted molecular weight ~41 kDa, commonly observed at 41-45 kDa.

UniProtKB · P41221

Protein Wnt-5a

WNT5A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P41221
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WNT5A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K4A4, Q6P278
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ChondrogenesisDifferentiationWnt signaling pathway

Molecular function

Developmental protein

Disease

Disease variantDwarfism

PTM

Disulfide bondGlycoproteinLipoprotein

Cellular component

Extracellular matrixSecreted

Technical term

Proteomics identificationReference proteome

Domain

Signal

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