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MOCS1 Antibody

CAT: 0800-RQ8828Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8828Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene. Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.
Specifications
Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
Q9NZB8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E.coli-derived human recombinant protein (amino acids E52-R584) was used as the immunogen for the MOCS1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, ELISA
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This MOCS1 antibody is available for research use only.
Storage Conditions
After reconstitution, the MOCS1 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MOCS1 antibody should be determined by the researcher.

UniProtKB · Q9NZB8

Molybdenum cofactor biosynthesis protein 1

MOCS1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZB8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MOCS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B3KPT7, B4DTP1, O14940, O14941, O75710, Q5J7W0, Q5TCE1, Q5TCE2, Q5TCE6, Q5TCE9, Q5TCF0, Q5TCF1, Q8N418, Q9NZB7, Q9UEM1
Protein keywords

Ligand

4Fe-4SGTP-bindingIronIron-sulfurMetal-bindingNucleotide-bindingS-adenosyl-L-methionine

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmMitochondrion

Disease

Disease variant

Molecular function

Lyase

Biological process

Molybdenum cofactor biosynthesis

Technical term

Proteomics identificationReference proteome

Domain

Transit peptide

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A69127-50ULMOCS1 Antibody

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