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PIK3AP1 Antibody

CAT: 0800-RQ8843Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8843Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K) ), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.
Specifications
Western blot: 1-2 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
Q6ZUJ8
Host
Rabbit
Reactivity
Human
Immunogen
An E.coli-derived human recombinant protein (amino acids H78-R583) was used as the immunogen for the PIK3AP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This PIK3AP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the PIK3AP1 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PIK3AP1 antibody should be determined by the researcher.

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