SORT1 Antibody / Sortilin

• Description:

  Altered expression or function of SORT1 has been associated with neurodegenerative disorders, cardiovascular disease, and lipid metabolism abnormalities. Research has linked SORT1 to regulation of low-density lipoprotein (LDL) cholesterol levels and to processes that influence neuronal growth and survival. Understanding SORT1's biological roles can provide insights into both neurological function and metabolic health. Using a high-quality SORT1 antibody enables reliable detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A SORT1 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies involving neuronal biology, lipid metabolism, and receptor-mediated signaling. Selecting the right SORT1 antibody is essential for generating accurate and consistent experimental results.

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  Q99523

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A peptide sequence specific to Sortilin was used as the immunogen for the SORT1 antibody.

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG

• Clone:

  17S35

• Applications:

  WB

• Purity:

  Affinity chromatography

• Format:

  Purified

• Limitations:

  This SORT1 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the SORT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the SORT1 antibody should be determined by the researcher.

• Image Legend:

  Western blot testing of human 1) K562, 2) HepG2, 3) U-251 and 4) MCF7 cell lysate with SORT1 antibody. Predicted molecular weight ~92 kDa.