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UCHL3 Antibody

CAT: 0800-RQ8920Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ8920Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UCHL3 is widely expressed across tissues and has been linked to key biological processes including DNA repair, cell cycle regulation, and stress responses. Dysregulation of UCHL3 has been associated with cancer, neurodegeneration, and impaired protein degradation pathways. Employing a UCHL3 antibody provides insights into its diverse cellular functions and disease associations. NSJ Bioreagents offers a high-quality UCHL3 antibody validated for applications such as western blot, immunohistochemistry, and immunoprecipitation. Using a UCHL3 antibody ensures sensitive and reproducible detection in studies of ubiquitin biology, proteostasis, and disease mechanisms.
Specifications
Western blot: 1:500, Immunofluorescence: 1:50
UniProt
P15374
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human UCHL3 was used as the immunogen for the UCHL3 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
26U65
Applications
WB, IF
Purity
Affinity purified
Format
Purified
Limitations
This UCHL3 antibody is available for research use only.
Storage Conditions
Store the UCHL3 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the UCHL3 antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm, Golgi
Image Legend
Immunofluorescent staining of FFPE human U-2 OS cells with UCHL3 antibody (green) and Alpha Tubulin mAb (red) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · P15374

Ubiquitin carboxyl-terminal hydrolase isozyme L3

UCHL3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15374
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
UCHL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
UCH-L3
EC number
3.4.19.12
Processing
—
Secondary accessions
B2R970, Q5TBK8, Q6IBE9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cytoplasm

Molecular function

HydrolaseProteaseThiol protease

PTM

Phosphoprotein

Biological process

Ubl conjugation pathway

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