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GMP Human BDNF Protein (E. coli)

CAT: 0716-GMP-BDFH15-500ugSize: 500 µgDry Ice: NoHazardous: No
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CAT#:0716-GMP-BDFH15-500ugSize:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent) .
Description
Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent) .
Specifications
This protein carries no "tag". The protein has a calculated MW of 13.6 kDa. The protein migrates as 15 kDa±3 kDa under reducing (R) condition, and 13 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE)
Expression Region
His 129 - Arg 247
Target
BDNF
Conjugation
Unconjugated
Tag
Native
Stability
-20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
Endotoxin
10 EU/mg
Purity
95%
Format
Powder-GMP
Buffer
0.1% TFA, pH2.2
Molecular Weight
13.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Blue ice
Storage Conditions
-20°C
Package Size
50ug*10
Host or Source
E. coli
Species
Human
Protein ID
P23560-1

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