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Anti-Syntaxin Antibody

CAT: 0942-1990-STXtSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0942-1990-STXtSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007) . Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010) .
Description
Our Anti-Syntaxin primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, rat, pig, and hamster Syntaxin and is Protein G purified. It is great for use in WB, IHC.
Synonyms
HPC 1 antibody, Neuron specific antigen HPC1 antibody, Neuron-specific antigen HPC-1 antibody, OTTHUMP00000174615 antibody, OTTHUMP00000174616 antibody, OTTHUMP00000174617 antibody, OTTHUMP00000174618 antibody, P35-1 antibody, STX1 antibody, STX1A antibody, STX1A_HUMAN antibody, SYN1A antibody, Syntaxin 1A (brain) antibody, Syntaxin 1A brain antibody, Syntaxin-1A antibody
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
STX1A
NCBI Gene ID
6804
UniProt
Q16623
Host
Mouse
Reactivity
Human, Rat, Pig, and Hamster
Immunogen
Synaptic immunoprecipitate (crude) from human brain.
Immunogen Type
Human
Target
Syntaxin
Clonality
Monoclonal
Clone
SP8
Conjugation
Unconjugated
Applications
ELISA, WB, IHC
Concentration
1 mg/ml
Format
Protein G Purified
Form
Liquid
Buffer
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Molecular Weight
36
Shipping Conditions
Blue Ice
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
IHC Dilution
1:100
WB Dilution
1:1000
Specificity
Specific for endogenous levels of the ~36 kDa syntaxin protein. The antibody has also been used for immunohistochemistry on formalin fixed, vibratome sections. *Does not work on paraffin sections.
Formulation
Protein G purified culture supernatant.
Quality Control
Western blots performed on each lot.
Isotype
IgG1

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