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Anti-Calbindin Antibody

CAT: 0942-302-CALBSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0942-302-CALBSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Calbindin (aka. calbindin D28k) is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. It is predominantly expressed in certain types of neurons, particularly in dendrites and perikarya of the cerebellum and is thought to buffer entry of calcium upon stimulation of glutamate receptors (Andressen et al., 1993) . Calbindin has recently been shown to play a critical role in mitochondrial dysfunction and loss of synaptic proteins in vivo in an Alzheimer’s disease mouse model (Kook et al., 2014) .
Description
Our Anti-Calbindin primary antibody from PhosphoSolutions is mouse monoclonal. It detects bovine, human, mouse, and rat Calbindin and is Protein G purified. It is great for use in WB, IHC.
Synonyms
Avian-type antibody, CAB27 antibody, CALB 1 antibody, CALB antibody, CALB1 antibody, CALB1_HUMAN antibody, Calbindin 1 28kDa antibody, Calbindin antibody, Calbindin D28 antibody, D 28K antibody, D-28K antibody, D28K antibody, OTTHUMP00000166027 antibody, OTTHUMP00000225441 antibody, RTVL H protein antibody, Vitamin D dependent calcium binding protein antibody, Vitamin D dependent calcium binding protein avian type antibody, Vitamin D-dependent calcium-binding protein antibody
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
CALB1
NCBI Gene ID
793
UniProt
P05937
Host
Mouse
Reactivity
Bovine, Human, Mouse, and Rat
Immunogen
Recombinant full length human calbindin purified from E. coli.
Immunogen Type
Human
Target
Calbindin
Clonality
Monoclonal
Clone
5A9
Conjugation
Unconjugated
Applications
ELISA, WB, IHC
Concentration
Lot Dependent
Format
Protein G Purified
Form
Liquid
Buffer
PBS + 50% glycerol and 5 mM NaN3
Molecular Weight
28
Shipping Conditions
Blue Ice
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
IHC Dilution
1:1000-1:5000
WB Dilution
1:2000
Specificity
Specific for endogenous levels of the ~28 kDa calbindin protein.
Formulation
Protein G purified.
Quality Control
Western blots performed on each lot.
Isotype
IgG2a

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