hsa-miR-451a antagomir

CAT:

804-HY-RI01139A-02

Size:

20 nmol

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UNSPSC Description: hsa-miR-451a antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Target Antigen: MicroRNA
Type: Oligonucleotides
Related Pathways: Epigenetics
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/hsa-mir-451a-antagomir.html
Solubility: 10 mM in H2O
Molecular Weight: 7414.826
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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