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Mer-NF5003F

CAT: 0804-HY-137985-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137985-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mer-NF5003F (Stachybotrydial; F 1839M), a sesquiterpene isolated from Stachybotrys, inhibits avian medulloblastoma virus (AMV) protease (IC50=7.8 μM) . Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50=0.61, 6.7, and 10 μg/mL, respectively), and fucosyltransferase (IC50=11.3 μg/mL) . Mer-NF5003F has in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multidrug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL) .
CAS Number
149598-70-9
Product Name Alternative
Stachybotrydial; F 1839M; Stachybotrydial
UNSPSC
12352005
Target
HSV; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mer-nf5003f.html
Smiles
O[C@@H]1CC[C@]2([C@]([H])(C1(C)C)CC[C@H]([C@@]23OC4=C(C3)C(O)=CC(C=O)=C4C=O)C)C
Molecular Formula
C23H30O5
Molecular Weight
386.48
References & Citations
[1]Kaneto, et al. Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp. J. Antibiot. (Tokyo) 47 (6), 727-730 (1994) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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