GMP Recombinant Human Transferrin (APO)

• Background:

  Serotransferrin belongs to transferrin family, and contains 2 transferrin-like domains. The protein is a secreted protein, and expressed by the liver and secreted in plasma. Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

• Product Name Alternative:

  Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF

• Accession Number:

  P02787

• Host:

  Mammalian cell

• Target:

  Transferrin (APO)

• Tag:

  Tag free

• Endotoxin:

  ≤0.5 EU/mg

• Purity:

  Greater than 95% as determined by reducing SDS-PAGE

• Activity:

  Measured in a serum-free cell proliferation assay using MDCK canine kidney epithelial cells. The ED50 for this effect is ≤5 μg/mL. Optimal concentration depends on cell type as well as the application or research objectives.

• Form:

  Lyophilized

• Buffer:

  Sterile water

• Reconstitution:

  Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

• Molecular Weight:

  75.2 kDa

• Shipping Conditions:

  The product is shipped with ice bag. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions:

  36 months at -20°C to -80°C in lyophilized state.6 months at -20°C to -80°C under sterile conditions after reconstitution.7-10 days at 2°C to 8°C under sterile conditions after reconstitution.Please minimize freeze-thaw cycles.

• Construct:

  Recombinant Human Transferrin (APO) is produced by our Mammalian cell expression system and the target gene encoding Val20-Pro698 is expressed.

• Species:

  Human