CD31 Mouse Monoclonal Antibody

• Background:

  PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

• Product Name Alternative:

  Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31

• Gene Name:

  CD31

• Gene ID:

  5175

• Swiss Prot:

  P16284

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100

• Form:

  Liquid

• Buffer:

  Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 83 kDa; Observed MW: 130 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  Mouse IgG1