ITGAM Mouse Monoclonal Antibody

• Background:

  This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3') . The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

• Product Name Alternative:

  CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6

• Gene Name:

  ITGAM

• Gene ID:

  3684

• Swiss Prot:

  P11215

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC, ELISA, FC

• Purification:

  Affinity Purification

• Dilution:

  IHC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

• Form:

  Liquid

• Buffer:

  Purified antibody in PBS with 0.05% sodium azide

• Modification:

  Unmodified

• Molecular Weight:

  127.1kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  Mouse IgG1