MCM2 Mouse Monoclonal Antibody

• Background:

  The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

• Product Name Alternative:

  BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN; KIAA0030; MGC10606

• Gene Name:

  MCM2

• Gene ID:

  4171

• Swiss Prot:

  P49736

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat, Monkey

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ELISA, FC

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

• Form:

  Liquid

• Buffer:

  Purified antibody in PBS with 0.05% sodium azide.

• Modification:

  Unmodified

• Molecular Weight:

  125kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  Mouse IgG1