NEFL Mouse Monoclonal Antibody

• Background:

  Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

• Product Name Alternative:

  NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110

• Gene Name:

  NEFL

• Gene ID:

  4747

• Swiss Prot:

  P07196

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat, Rabbit

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ELISA, FC

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:500, ELISA 1:5000-1:20000, FC 1:200-1:400

• Form:

  Liquid

• Buffer:

  Purified antibody in PBS with 0.05% sodium azide

• Modification:

  Unmodified

• Molecular Weight:

  61.5kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  Mouse IgG1