HSP90 α (1F6) Mouse Monoclonal Antibody

• Background:

  The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence., function:Molecular chaperone., function:Molecular chaperone. Has ATPase activity., similarity:Belongs to the heat shock protein 90 family., subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV., subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.

• Product Name Alternative:

  Heat shock protein HSP 90-alpha (Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38)

• Gene Name:

  HSP90AA1

• Gene ID:

  3320

• Swiss Prot:

  P07900

• Host:

  Mouse

• Reactivity:

  Human, Rat, Mouse

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, ICC/IF

• Field of Research:

  Antigen processing and presentation; NOD-like receptor; Progesterone-mediated oocyte maturation; Pathways in cancer; Prostate cancer

• Purification:

  Affinity purification

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200

• Form:

  Liquid

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

• Modification:

  Unmodified

• Molecular Weight:

  95kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG